SPACE Tool, or the STI Prevention Allocation Consequences Estimator, is a tool created for federally funded jurisdictions (i.e., states and directly funded large cities) to estimate the impact of changes in STI prevention budgets on the incidence and direct medical costs of bacterial STIs and STI-attributable HIV infection. Estimating these effects is not an exact science; however, SPACE Tool helps STI prevention personnel make evidence-based calculations that show how budget changes impact disease burden and direct medical costs. More information describing the methods for this tool can be found in the SPACE Tool 2.0 manuscript. SPACE Tool 2.0 is an updated version from the model initially developed in 2017 that incorporates updated parameters and scientific methods, a new interface that was designed to be user-friendly and engaging, and new functionalities requested by model users.