In 2018, youth aged 13 to 24 made up 21% (7,807) of the 37,832 new HIV diagnoses in the United States. The goal of EHE to reduce new HIV infections by 90% in 10 years includes reducing incidence among youth. This project aims to estimate the impact of HIV incidence among adolescents and to address the “Treatment” and “Prevention” pillars of ending the HIV epidemic (EHE) by quantifying their relative impact in terms of reductions in incidence. This project will also estimate the level of additional PrEP coverage needed to reduce incidence among adolescents over a ten-year period and will include simulations to determine expected increases in viral suppression and reductions in incidence if the continuum of care were to be improved to the degree demonstrated in empirical intervention studies.