Agent-based MSM sexual network modeling for complex prevention questions

The questions explored in this project all relate to understanding the interlocking relationships between HIV prevention methods (primarily pre-exposure prophylaxis, or PrEP), and STD transmission and treatment, to understand the future course of the HIV and STD epidemics for men who have sex with men (MSM) overall and by race. Because of the complex feedback and high-dimensionality of the behaviors and subgroups of interest, and the infeasibility of conducting randomized trials to probe the questions of interest, agent-based modeling is well-suited. Agent-based models of MSM have been developed to represent the epidemics in Atlanta, GA and Baltimore, MD. This project is conducted in partnership with scientists in the Divisions of HIV/AIDS Prevention and STD Prevention.

Modeling an Integrated HIV Prevention and Care Continuum to Achieve the Ending the HIV Epidemic Goals

Jenness S,Johnson J,Hoover K,Smith D,Delaney K

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Modeling the Impact of PrEP Programs for Adolescent Sexual Minority Males Based on Empirical Estimates for the PrEP Continuum of Care

Hamilton D,Rosenberg E,Sullivan P,Wang L,Dunville R,Barrios L,Aslam M,Mustanski B,Goodreau S

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New publication, “Modeling the joint effects of adolescent and adult PrEP for sexual minority males in the United States”

Hamilton D,Rosenberg E,Jenness S,Sullivan P,Wang L,Dunville R,Barrios L,Aslam M,Goodreau S

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Effectiveness Model of PrEP by Age, Race, and Location

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Comprehensive HIV Prevention for MSM in the United States

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Longitudinal Variation in HIV PrEP Uptake, Adherence, and Discontinuation Among MSM

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The Cost-Effectiveness of STI Programs to Reduce HIV Incidence Among MSM: A Modeling Analysis

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Impact of DIS Interventions with MSM

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Programs on HIV Incidence in a Dynamic Sexual Network of Men Who Have Sex with Men

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Impact of CDC PrEP guidelines and uptake on racial disparities among MSM

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Optimizing Coverage vs Frequency for Sexually Transmitted Infection Screening of Men Who Have Sex With Men cost-effectiveness of the CDC’s STI screening recommendations among men who have sex with men in the United States: A modeling study

Weiss K,Jones J,Anderson E,Gift T,Chesson H,Bernstein K,Workowski K,Tuite A,Rosenberg E,Sullivan P,Jenness S

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Epidemiological impact of implementing expedited partner therapy for STI prevention among men who have sex with men in the United States: A modeling study

Weiss K,Jones J,Katz D,Gift T,Bernstein K,Workowski K,Rosenberg E,Jenness S

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Gonorrhea and chlamydia diagnosis as an entry point for HIV pre-exposure prophylaxis: A modeling study

Kasaie P,Schumacher C,Jennings J,Berry S,Tuddenham S,Shah M,Rosenberg E,Hoover K,Gift T,Chesson H,German D,Dowdy D

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Proportion of incident HIV cases among men who have sex wth men attributable to gonorrhea and chlamydia: A modeling analysis

Jones J,Weiss K,Dietz P,Rosenberg E,Gift T,Chesson H,Sullivan P,Lyles C,Bernstein K,Jenness S

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Addressing Gaps in HIV Preexposure Prophylaxis Care to Reduce Racial Disparities in HIV Incidence in the United States

Jenness S,Maloney K,Smith D,Hoover K,Goodreau S,Weiss K,Sullivan P,Liu A,Rao D,Rosenberg E

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Individual HIV Risk versus Population Impact of Risk Compensation after HIV Preexposure Prophylaxis Initiation

Jenness S,Sharma A,Goodreau S,Rosenberg E,Weiss K,Hoover K,Smith D,Sullivan P

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Impact of providing Preexposure prophylaxis for HIV at clinics for sexually transmitted infections in Baltimore city: an agent-based model

Kasaie P,Berry S,Shah M,Rosenberg E,Hoover K,Gift T,Chesson H,Pennington J,German D,Flynn C,Beyrer C,Dowdy D

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Impact of the Centers for Disease Control’s HIV Preexposure Prophylaxis Guidelines for Men Who Have Sex With Men in the United States

Jenness S,Goodreau S,Rosenberg E,Beylerian E,Hoover K,Smith D,Sullivan P

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Incidence of Gonorrhea and Chlamydia Following Human Immunodeficiency Virus Preexposure Prophylaxis among Men Who Have Sex with Men: A Modeling Study

Jenness S,Weiss K,Goodreau S,Gift T,Chesson H,Hoover K,Smith D,Liu A,Sullivan P,Rosenberg E

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Optimal costs of HIV pre-exposure prophylaxis for men who have sex with men

McKenney J,Chen A,Hoover K,Kelly J,Dowdy D,Kasaie P,Sullivan P,Rosenberg E

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Distribution of HIV Transmission by Network and Clinical Factors Among US MSM

Chapin Bardales J,Jenness S,Rosenberg E,Sullivan P,Goodreau S

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Measuring the Impact of Screening Guidelines (and other interventions) on STDs in MSM

Weiss K,Jones J,Anderson E,Gift T,Chesson H,Bernstein K,Workowski K,Hoover K,Tuite A,Rosenberg E,Jenness S

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Comparing the Effects of STI Prevention Programs on HIV Incidence in a Dynamic Sexual Network of Men Who Have Sex with Men

Jones J

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